Fresno () is a major city in the San Joaquin Valley of California, United States. It is the county seat of Fresno County and the largest city in the greater Central Valley region. It covers about 115 square miles (300 km2) and had a population of 542,107 in 2020, making it the fifth-most populous city in California, the most populous inland city in California, and the 34th-most populous city in the nation.[11][7][12] The Metro population of Fresno is 1,008,654 as of 2022. [1